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WELCOME!   The Castillo Laboratory for Mechanobiology & Regenerative Medicine studies interactions between mechanobiological cues and the musculoskeletal system with the long-term goal of developing novel biophysical, pharmaceutical, and stem cell-based interventions to improve musculoskeletal health. We use in vivo and in vitro approaches including engineering tools and analyses, state-of-the-art cell and molecular biology techniques, and translational experimentation to identify, characterize, and manipulate key mechanisms by which multi-potent stem cells and lineage-determined cells sense and respond to mechanical and biochemical stimuli. Our research facilities are located at the NYU Bioengineering Institute and at the Veterans Affairs Medical Center, Manhattan Campus. We are grateful for funding from the Department of Veterans Affairs, the AO Foundation, the NYU Center for Skeletal and Craniofacial Biology, and the NYU Clinical and Translational Science Institute.

 

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